Effect of Leptadenia hastata (Pers) Decne on Metabolic Profile of Pregnant Albino Rats
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چکیده
Vegetables consumption has been associated with lower risk of pre eclempsia in pregnancy. The aim of this study is to determine the effect of Leptadenia hastata (Pers) Decne on some biochemical parameters in pregnant rats. Leptadenia hastata (Pers) Decne is a tropical herb widely used by pregnant women in northern Nigeria with so much nutritive and therapeutic claims attributed to it. The effect of different doses of the plant on metabolic profile of pregnant rats was determined. Results obtained showed significant decrease (p≤0.05) in Fasting Blood Sugar (FBS), Total Cholesterol (TC), Triglycerides (TG) and Low Density Lipoprotein (LDL) values. Urea, creatinine and alanine aminotransferase (ALT) levels increased significantly (p≤0.05) in a dose depended manner while aspartate aminotranferase (AST) activity showed little or no change in activity. The study proved the hypolipidemic effect of L. hastata and provided a scientific support for the ethno medical uses of L. hastata in the management of pre eclempsia in the study area.
منابع مشابه
Leptadenia hastata: A Review of its Traditional uses and its Pharmacological Activity
Leptadenia hastata (Pers.) Decne is often used traditionally for hypertension, catarrh, skin diseases, woundhealing, prostate complaints and as an aphrodisiac. In traditional systems of medicine, different parts are used including the leaves, latex, roots and even whole plant. Leptadenia hastata is reported to contain alkaloids, saponins, phenolic glycosides, tannins, flavonoids, proanthocyanid...
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تاریخ انتشار 2014